Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 122
interventional 68
Observational 44
Registry 10

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 18
Drug|placebo 14
Other 12
Behavioral 6
Device 6
Dietary Supplement 3
Procedure 2
Behavioral|Diagnostic Test|Dietary Supplement|Procedure 1
Biological 1
Biological|placebo 1
Device|Other 1
Dietary Supplement|Other 1
Dietary Supplement|placebo 1
Genetic 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 19
United Kingdom 5
Denmark 4
Spain 4
Brazil 3
France 3
Germany 3
NA 3
Netherlands 3
Canada 2
United States|Israel 2
Belgium|Denmark|France|Germany|Netherlands|United Kingdom 1
Greece 1
Hong Kong 1
Israel 1
Italy 1
Japan 1
Japan|United States|Australia|Brazil|Bulgaria|Canada|China|Hong Kong|India|Jordan|Korea, Republic of|Malaysia|Mexico|Poland|Puerto Rico|Russian Federation|Sri Lanka|Taiwan|Thailand|Turkey 1
Norway 1
Poland 1
United States|Australia|Belgium|Brazil|Bulgaria|Canada|Chile|Czechia|France|Germany|Israel|Italy|Korea, Republic of|Poland|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
United States|Australia|Belgium|Brazil|Canada|Chile|Czechia|France|Germany|Israel|Italy|Korea, Republic of|Poland|Spain|Sweden|Switzerland|Turkey|United Kingdom 1
United States|Australia|Brazil|Czechia|France|Germany|Italy|Japan|Korea, Republic of|Mexico|Sweden 1
United States|Bulgaria|Canada|France|Israel|Italy|United Kingdom 1
United States|Canada 1
United States|Canada|France|Germany 1
United States|Denmark 1
United States|France|United Kingdom 1

Sites per Study

Site_count Study_Count
1 45
2 7
3 1
4 3
7 2
8 2
9 1
13 1
17 1
35 1
55 1
58 1
80 1
86 1

Phase

Phase Study_Count
N/A 32
Phase 2 10
Phase 1 8
Phase 3 8
Phase 1/Phase 2 5
Phase 4 5

Number of Arms

Number_of_Arms Count_of_Studies
1 16
2 33
3 10
4 1
5 1
8 1
NA 6

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.3 Phase.4
Min. 1.0000 4.000 7.0 8.0 25.00 6.00
1st Qu. 19.0000 9.000 18.0 19.5 134.75 9.00
Median 23.5000 19.500 24.0 38.0 186.50 25.00
Mean 71.0625 22.875 29.6 62.7 204.50 27.25
3rd Qu. 52.5000 26.000 36.0 57.5 235.00 43.25
Max. 456.0000 72.000 63.0 250.0 519.00 53.00

Trial Group Type

group_type Group_Count
Experimental 76
Placebo Comparator 22
Active Comparator 16
No Intervention 13
NA 6
Other 1
Sham Comparator 1

Intervention Model

intervention_model Study_Count
Parallel Assignment 37
Single Group Assignment 21
Crossover Assignment 4
Sequential Assignment 3
NA 2
Factorial Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 42
Diagnostic 9
Other 5
Basic Science 4
Supportive Care 4
Prevention 3
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 19
NA 4
Denmark 3
United Kingdom 3
France 2
Germany 2
Brazil 1
Egypt 1
Italy 1
Singapore 1
Singapore|Australia|Brazil 1
Switzerland 1
Turkey 1
United States|Austria|China|France|Germany|Italy|Japan|Netherlands|United Kingdom 1
United States|Belgium|Canada|France|Germany|Italy|Spain 1
United States|Canada|France|Germany|United Kingdom 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 39
4 1
8 2
13 1
15 1

Enrollment Metrics

Measure Observational
Min 10.0000
1st Qu 35.0000
Median 80.0000
Mean 594.0698
3rd Qu 198.5000
Max 6000.0000

Observation Model

observational_model Study_Count
Cohort 23
Case-Only 6
Case-Control 5
Other 4
NA 3
Family-Based 2
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 20
Cross-Sectional 12
Other 4
Retrospective 4
NA 4

Registries

Studies by Country

Country Study_Count
United Kingdom 4
China 1
Egypt 1
NA 1
United States 1
United States|Australia 1
United States|Bulgaria|Canada|France|United Kingdom 1

Sites per Study

Site_count Study_Count
1 8
2 1
5 1

Enrollment Metrics

Measure Registries
Min 25.0
1st Qu 225.0
Median 334.5
Mean 2577.4
3rd Qu 875.0
Max 20000.0

Registry Model

observational_model Study_Count
Cohort 5
Case-Only 3
Other 2

Time Perspective

time_perspective Study_Count
Prospective 10

Follow-up

target_duration Study_Count
5 Years 5
1 Day 1
1 Year 1
100 Years 1
15 Years 1
3 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04141670 S 48168 (ARM 210) for the Treatment of RYR1-related Myopathies (RYR1-RM) https://ClinicalTrials.gov/show/NCT04141670 Recruiting Armgo Pharma, Inc. 2021-05-30
NCT04033159 Early Phase Human Drug Trial to Investigate Dynamin 101 (DYN101) in Patients ≥ 16 Years With Centronuclear Myopathies https://ClinicalTrials.gov/show/NCT04033159 Recruiting Dynacure SAS 2022-04-30
NCT03979157 Non-invasive Molecular Imaging of Muscle Structure (MSOT_muscles) https://ClinicalTrials.gov/show/NCT03979157 Completed University of Erlangen-Nürnberg Medical School 2019-11-11
NCT03406780 A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy https://ClinicalTrials.gov/show/NCT03406780 Completed Capricor Inc. 2020-03-10
NCT03199469 Gene Transfer Clinical Study in X-Linked Myotubular Myopathy https://ClinicalTrials.gov/show/NCT03199469 Active, not recruiting Audentes Therapeutics 2024-03-31
NCT03179631 Long-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy https://ClinicalTrials.gov/show/NCT03179631 Recruiting PTC Therapeutics 2023-09-05
NCT03267277 Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis https://ClinicalTrials.gov/show/NCT03267277 Recruiting National Institutes of Health Clinical Center (CC) 2022-07-31
NCT03092167 Physical Training in Patients With Idiopathic Inflammatory Myopathies https://ClinicalTrials.gov/show/NCT03092167 Recruiting University of Sao Paulo 2022-01-31
NCT02971683 Trial to Evaluate the Efficacy and Safety of Abatacept in Combination With Standard Therapy Compared to Standard Therapy Alone in Improving Disease Activity in Adults With Active Idiopathic Inflammatory Myopathy https://ClinicalTrials.gov/show/NCT02971683 Active, not recruiting Bristol-Myers Squibb 2020-06-17
NCT02810028 Acceptance and Commitment Therapy for Muscle Disease https://ClinicalTrials.gov/show/NCT02810028 Completed King’s College Hospital NHS Trust 2018-04-30
NCT02436096 A Study to Evaluate eFFIcacy and Safety of Sublingual TNX-102 SL Tablet Taken at Bedtime in Patients With fibRoMyalgia https://ClinicalTrials.gov/show/NCT02436096 Completed Tonix Pharmaceuticals, Inc. 2016-09-30
NCT02377921 Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Sialic Acid in Patients With Glucosamine (UDP-N-acetyl)-2-epimerase Myopathy (GNEM) or Hereditary Inclusion Body Myopathy (HIBM) https://ClinicalTrials.gov/show/NCT02377921 Completed Ultragenyx Pharmaceutical Inc 2017-06-09
NCT02367014 Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy https://ClinicalTrials.gov/show/NCT02367014 Completed Stealth BioTherapeutics Inc. 2016-04-30
NCT02362425 Antioxidant Therapy in RYR1-Related Congenital Myopathy https://ClinicalTrials.gov/show/NCT02362425 Completed National Institutes of Health Clinical Center (CC) 2018-05-30
NCT02358512 Intermittent Versus Continuous Feeding in ICU Patients https://ClinicalTrials.gov/show/NCT02358512 Completed Guy’s and St Thomas’ NHS Foundation Trust 2018-01-31
NCT02318875 Investigation of Kritech Efficacy on Subjects Having Functional Discomfort Associated to Joints and Muscles Disorders https://ClinicalTrials.gov/show/NCT02318875 Completed Vivatech 2013-06-30
NCT02255422 RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR https://ClinicalTrials.gov/show/NCT02255422 Completed Reata Pharmaceuticals, Inc. 2017-11-02
NCT02100241 Effectiveness Analysis of Active Stretching Versus Active Stretching With Low Frequency Currents https://ClinicalTrials.gov/show/NCT02100241 Completed Rodríguez, Francisco Piqueras, M.D. 2012-04-30
NCT02090959 An Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy https://ClinicalTrials.gov/show/NCT02090959 Completed PTC Therapeutics 2018-06-21
NCT03384420 A Study to Evaluate the Safety and Therapeutic Effects of Transplantation of MNV-BM-BLD in Pediatric Patients With Pearson Syndrome https://ClinicalTrials.gov/show/NCT03384420 Enrolling by invitation Minovia Therapeutics Ltd. 2021-06-01
NCT02078076 IRM Cardiaque en Respiration Libre Pour Des Patients Atteints de Dystrophinopathie sévère https://ClinicalTrials.gov/show/NCT02078076 Completed Institut National de la Santé Et de la Recherche Médicale, France 2015-11-30
NCT01270269 ACT-ICU Study: Activity and Cognitive Therapy in the Intensive Care Unit https://ClinicalTrials.gov/show/NCT01270269 Completed Vanderbilt University Medical Center 2013-03-31
NCT02020187 Aerobic Training in Patients With Congenital Myopathies https://ClinicalTrials.gov/show/NCT02020187 Completed Rigshospitalet, Denmark 2014-11-30
NCT02011282 Electro-Neuro-Muscular Stimulation in ICU https://ClinicalTrials.gov/show/NCT02011282 Completed University of Thessaly 2015-03-31
NCT01895283 The Effect of Aerobic Exercise, on Fitness and Functional Muscle Strength, in Patients With Muscular Dystrophy https://ClinicalTrials.gov/show/NCT01895283 Completed Rigshospitalet, Denmark 2014-12-31
NCT01830972 An Open Label Phase 2 Extension Study of Higher Dose Sialic Acid-Extended Release (SA-ER) Tablets and Sialic Acid-Immediate Release (SA-IR) Capsules in Patients With Glucosamine (UDP-N-acetyl)-2-Epimerase (GNE) Myopathy https://ClinicalTrials.gov/show/NCT01830972 Completed Ultragenyx Pharmaceutical Inc 2017-02-14
NCT01826487 Phase 3 Study of Ataluren in Patients With Nonsense Mutation Duchenne Muscular Dystrophy https://ClinicalTrials.gov/show/NCT01826487 Completed PTC Therapeutics 2015-08-31
NCT01634750 Phase I Clinical Trial of ManNAc in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM) https://ClinicalTrials.gov/show/NCT01634750 Completed National Institutes of Health Clinical Center (CC) NA
NCT01527318 The Effect of Fibrate Therapy in Two Patients With Neutral Lipid Storage Disease With Myopathy (NLSDM) https://ClinicalTrials.gov/show/NCT01527318 Completed Maastricht University Medical Center 2012-12-31
NCT01517880 A Phase 2 Study to Evaluate the Dose and Pharmacodynamic Efficacy of Sialic Acid-Extended Release (SA-ER) Tablets in Patients With GNE Myopathy or Hereditary Inclusion Body Myopathy https://ClinicalTrials.gov/show/NCT01517880 Completed Ultragenyx Pharmaceutical Inc 2013-11-30
NCT03268421 Fibromyalgia Integrative Training for Adolescents With Juvenile Fibromyalgia https://ClinicalTrials.gov/show/NCT03268421 Recruiting Children’s Hospital Medical Center, Cincinnati 2022-10-31
NCT01359319 Safety and Pharmacokinetics of Sialic Acid Tables in Patients With Hereditary Inclusion Body Myopathy (HIBM) https://ClinicalTrials.gov/show/NCT01359319 Completed Ultragenyx Pharmaceutical Inc 2012-04-30
NCT04262570 Evaluation of Therapeutic Response in Spinal Muscular Atrophy Using Multispectral Optoacoustic Tomography (MSOT) and Magnetic Resonance Imaging (MRI) https://ClinicalTrials.gov/show/NCT04262570 Recruiting University of Erlangen-Nürnberg Medical School 2021-12-31
NCT04262258 Effects of a Blueberry Enriched Diet on the Skeletal Muscle Regenerative Process https://ClinicalTrials.gov/show/NCT04262258 Completed Cornell University 2019-12-31
NCT04115475 New Imaging Biomarkers for Muscular Diseases - Multispectral Optoacoustic Imaging in Spinal Muscular Atrophy https://ClinicalTrials.gov/show/NCT04115475 Active, not recruiting University of Erlangen-Nürnberg Medical School 2020-01-30
NCT04025632 Safety and Efficacy Study of Zilucoplan in Subjects With Immune-Mediated Necrotizing Myopathy https://ClinicalTrials.gov/show/NCT04025632 Recruiting Ra Pharmaceuticals 2020-11-30
NCT03973203 Niacin Supplementation in Healthy Controls and Mitochondrial Myopathy Patients https://ClinicalTrials.gov/show/NCT03973203 Completed University of Helsinki 2017-12-31
NCT03918356 Application of Electrical Impedance Myography (EIM) as a Potential Biomarker of Idiopathic Inflammatory Myopathies https://ClinicalTrials.gov/show/NCT03918356 Recruiting Yale University 2020-06-30
NCT03888716 A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease https://ClinicalTrials.gov/show/NCT03888716 Recruiting NeuroVive Pharmaceutical AB 2020-03-18
NCT03862846 A Study of the Safety of REN001 in Patients With Primary Mitochondrial Myopathy https://ClinicalTrials.gov/show/NCT03862846 Active, not recruiting Reneo Pharma Ltd 2020-06-30
NCT03813485 Electromyographic´s Differences Between Dry Needling in Tonic or Phasic Skeletal Muscle Fibers. https://ClinicalTrials.gov/show/NCT03813485 Recruiting Universidad Francisco de Vitoria 2019-04-10
NCT03751644 Peripherical Neuromuscular Electrical Stimulation in Systemic Autoimmune Myopathies https://ClinicalTrials.gov/show/NCT03751644 Recruiting University of Sao Paulo 2021-11-01
NCT03749538 Transcranial Current Stimulation in Patients With Systemic Autoimmune Myopathies https://ClinicalTrials.gov/show/NCT03749538 Recruiting University of Sao Paulo 2020-10-01
NCT03728803 Inspiratory Muscle Training in Nemaline Myopathy https://ClinicalTrials.gov/show/NCT03728803 Recruiting Radboud University 2020-07-31
NCT03728777 Resveratrol Supplementation in Patients With Mitochondrial Myopathies and Skeletal Muscle Fatty Acid Oxidation Disorders https://ClinicalTrials.gov/show/NCT03728777 Completed Rigshospitalet, Denmark 2019-10-01
NCT03715777 Electromyographic Study for the Help and Guidance of BoNTA Administration in the Treatment of Chronic Pelvic Floor Pain https://ClinicalTrials.gov/show/NCT03715777 Recruiting Instituto de Investigacion Sanitaria La Fe 2019-04-01
NCT03693898 MR in Patients With Collagen VI Related Myopathies https://ClinicalTrials.gov/show/NCT03693898 Recruiting Rigshospitalet, Denmark 2019-05-01
NCT03627962 Oculomotor Training and Chinese Characters Recognition in Children With Neuromuscular Disease https://ClinicalTrials.gov/show/NCT03627962 Completed The Hong Kong Polytechnic University 2017-04-30
NCT03556150 Effectiveness of a Manual Therapy Protocol in Patients With Masticatory Muscle Disorders https://ClinicalTrials.gov/show/NCT03556150 Completed University of Alcala 2018-09-03
NCT03547687 Neurosciences-Intensive Care Unit Electrical Stimulation https://ClinicalTrials.gov/show/NCT03547687 Completed Oregon Health and Science University 2019-12-31
NCT03531554 Acute Nutritional Ketosis in VLCAD Deficiency https://ClinicalTrials.gov/show/NCT03531554 Completed University Medical Center Groningen 2017-03-31
NCT03440034 Study of Pioglitazone in Sporadic Inclusion Body Myositis https://ClinicalTrials.gov/show/NCT03440034 Active, not recruiting Johns Hopkins University 2020-12-31
NCT01259791 Evaluation of Patients With Statin Myopathy Using an N of 1 Trial Design https://ClinicalTrials.gov/show/NCT01259791 Completed Lawson Health Research Institute 2013-08-31
NCT01236898 Pharmacokinetic Study on N-acetylneuraminic Acid https://ClinicalTrials.gov/show/NCT01236898 Completed Tohoku University 2011-06-30
NCT00976807 Rehabilitation Following Critical Illness https://ClinicalTrials.gov/show/NCT00976807 Completed Guy’s and St Thomas’ NHS Foundation Trust 2012-11-30
NCT00952900 An Implementation and Biobehavioral Study of Temporomandibular Joint and Muscle Disorder (TMJMD) https://ClinicalTrials.gov/show/NCT00952900 Completed The University of Texas at Arlington 2013-10-31
NCT00937001 Critical Illness Myopathy as a Cause of Debilitating ICU-Acquired Weakness https://ClinicalTrials.gov/show/NCT00937001 Active, not recruiting Vanderbilt University Medical Center 2010-01-31
NCT03653663 NIRS to Diagnose SAMS https://ClinicalTrials.gov/show/NCT03653663 Active, not recruiting Hartford Hospital 2020-02-29
NCT01438788 Low Protein Diet in Patients With Collagen VI Related Myopathies https://ClinicalTrials.gov/show/NCT01438788 Completed Istituto Ortopedico Rizzoli 2013-06-30
NCT02346461 An Open Label Phase 2 Study of ManNAc in Subjects With GNE Myopathy https://ClinicalTrials.gov/show/NCT02346461 Completed National Institutes of Health Clinical Center (CC) 2017-12-30
NCT02101632 Myorelaxant Effect of Bee Venom(BV) Topical Skin Application in Patients With RDC/TMD Ia and Ib https://ClinicalTrials.gov/show/NCT02101632 Completed Medical University of Silesia 2014-03-31
NCT00609063 The Effect of Statin Medications on Muscle Performance (The STOMP Study) https://ClinicalTrials.gov/show/NCT00609063 Completed Hartford Hospital 2011-06-30
NCT00285181 Effects of Statins on Pro- and Antioxidant Status : Link With Statin-Associated Myopathy. https://ClinicalTrials.gov/show/NCT00285181 Completed University Hospital, Montpellier NA
NCT00199745 Differences in Atorvastatin Metabolite Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity https://ClinicalTrials.gov/show/NCT00199745 Completed Oslo University Hospital 2008-12-31
NCT00195637 Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy https://ClinicalTrials.gov/show/NCT00195637 Completed National Institutes of Health Clinical Center (CC) 2006-07-03
NCT00120055 Association Between Systemic Exposure of Atorvastatin and Metabolites and Atorvastatin-induced Myotoxicity https://ClinicalTrials.gov/show/NCT00120055 Completed University of Oslo School of Pharmacy NA
NCT00312234 Qigong vs. Aerobic Exercise in the Treatment of Childhood Chronic Musculoskeletal Pain https://ClinicalTrials.gov/show/NCT00312234 Completed The Hospital for Sick Children 2007-08-31
NCT00004770 Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy https://ClinicalTrials.gov/show/NCT00004770 Completed Office of Rare Diseases (ORD) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03897803 Elastography in Patients With Idiopathic Inflammatory Myopathies https://ClinicalTrials.gov/show/NCT03897803 Recruiting Benha University 2020-09-15
NCT03819959 Metabolomics Study on Intensive Care Acquired Muscle Weakness in Polytrauma https://ClinicalTrials.gov/show/NCT03819959 Recruiting Technische Universität München 2021-01-01
NCT03250988 Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility https://ClinicalTrials.gov/show/NCT03250988 Completed Vanderbilt University Medical Center 2018-08-01
NCT03211923 Muscle Relaxation in Myopathies With Positive Muscle Phenomena https://ClinicalTrials.gov/show/NCT03211923 Enrolling by invitation Radboud University 2019-12-31
NCT03211390 Using Telemedicine to Improve Spasticity Diagnosis Rates https://ClinicalTrials.gov/show/NCT03211390 Completed Vanderbilt University Medical Center 2018-08-01
NCT03209960 Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity https://ClinicalTrials.gov/show/NCT03209960 Completed Vanderbilt University Medical Center 2018-08-01
NCT03092180 Optimizing Treatment on Idiopathic Inflammatory Myopathies https://ClinicalTrials.gov/show/NCT03092180 Recruiting University of Sao Paulo 2019-01-31
NCT03042286 SAPhIRE Statin Adverse Drug Reaction https://ClinicalTrials.gov/show/NCT03042286 Recruiting National Heart Centre Singapore 2020-01-31
NCT03018184 Contractile Cross Sectional Areas and Muscle Strength in Patients With Congenital Myopathies https://ClinicalTrials.gov/show/NCT03018184 Active, not recruiting Rigshospitalet, Denmark 2018-08-31
NCT02918032 International Registry Study of Neutral Lipid Storage Disease (NLSD) / Triglyceride Deposit Cardiomyovasculopathy (TGCV) and Related Diseases https://ClinicalTrials.gov/show/NCT02918032 Recruiting Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 2020-10-31
NCT02911896 Physical Function in Critical Care (PaciFIC) https://ClinicalTrials.gov/show/NCT02911896 Completed University of Melbourne 2016-12-31
NCT02897921 Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS) https://ClinicalTrials.gov/show/NCT02897921 Active, not recruiting Rigshospitalet, Denmark 2020-05-31
NCT02895789 Oxidative Capacity and Exercise Tolerance in Ambulatory SMA https://ClinicalTrials.gov/show/NCT02895789 Recruiting Columbia University 2020-04-30
NCT02704273 A Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects https://ClinicalTrials.gov/show/NCT02704273 Completed Audentes Therapeutics 2019-09-30
NCT02057705 Prospective, Longitudinal Study of the Natural History and Functional Status of Patients With Myotubular Myopathy (MTM) https://ClinicalTrials.gov/show/NCT02057705 Completed Valerion Therapeutics, LLC 2017-06-26
NCT00341679 Studies of the Natural History and Pathogenesis of Autoimmune/Connective Tissue Diseases https://ClinicalTrials.gov/show/NCT00341679 Completed National Institutes of Health Clinical Center (CC) NA
NCT02453152 Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM) https://ClinicalTrials.gov/show/NCT02453152 Completed University of Florida 2019-07-31
NCT02362685 Metabolic Exercise Testing https://ClinicalTrials.gov/show/NCT02362685 Recruiting University Hospital, Brest 2027-12-31
NCT02231697 A Medical Chart Review of Patients With X-Linked Myotubular Myopathy (XLMTM) https://ClinicalTrials.gov/show/NCT02231697 Completed Audentes Therapeutics 2019-12-31
NCT03354767 The Role of Ischaemia-reperfusion Injury in the Pathogenesis of Muscle Wasting After Thoracic Aortic Surgery https://ClinicalTrials.gov/show/NCT03354767 Completed Imperial College London 2014-10-31
NCT01902940 Natural History in CCFDN and IBM Syndromes https://ClinicalTrials.gov/show/NCT01902940 Completed Ludwig-Maximilians - University of Munich 2013-09-30
NCT01840657 Myotubular Myopathy Event Study https://ClinicalTrials.gov/show/NCT01840657 Completed Cure CMD 2015-10-31
NCT01817946 Myotubular Myopathy Genetic Testing Study https://ClinicalTrials.gov/show/NCT01817946 Completed Cure CMD 2017-03-31
NCT01568658 Genetic and Physical Study of Childhood Nerve and Muscle Disorders https://ClinicalTrials.gov/show/NCT01568658 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT01553396 Muscle Strength and Functional Autonomy of Elderly Women https://ClinicalTrials.gov/show/NCT01553396 Completed Euro-American Network of Human Kinetics 2009-02-28
NCT01459302 Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders https://ClinicalTrials.gov/show/NCT01459302 Recruiting University of Massachusetts, Worcester 2021-10-31
NCT01451281 Studying Skeletal Muscle, Heart, and Diaphragm Imaging in Boys With Duchenne Muscular Dystrophy https://ClinicalTrials.gov/show/NCT01451281 Completed National Institutes of Health Clinical Center (CC) NA
NCT01417533 A Natural History Study of Patients With GNE Myopathy https://ClinicalTrials.gov/show/NCT01417533 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT01364714 Biomechanical Properties in Intensive Care Unit (ICU) Survivors 12-month After Discharge https://ClinicalTrials.gov/show/NCT01364714 Completed Rigshospitalet, Denmark 2011-02-28
NCT01353430 Characterization of Inclusion Body Myopathy Associated With Paget’s Disease of Bone and Frontotemporal Dementia (IBMPFD) https://ClinicalTrials.gov/show/NCT01353430 Recruiting University of California, Irvine 2025-12-31
NCT04193943 Validation of Simplified Electrophysiological Examination in the Diagnosis of Critical Illness Myopathy or Neuropathy https://ClinicalTrials.gov/show/NCT04193943 Active, not recruiting Università degli Studi di Brescia 2014-11-26
NCT03998540 Improvement of DIAgnostic and Phenotype-genotype Correlation Studies in Patients With MYOpathy Suspected of TITinopathy https://ClinicalTrials.gov/show/NCT03998540 Recruiting University Hospital, Montpellier 2021-06-30
NCT03936920 Intra and Inter Reliability and Validity of the Turkish Version of Ottowa Sitting Scale in Intensive Care Unit Survivors https://ClinicalTrials.gov/show/NCT03936920 Active, not recruiting Izmir Katip Celebi University 2019-08-31
NCT03753412 Recovery From ICUAW Following Severe Respiratory and Cardiac Failure https://ClinicalTrials.gov/show/NCT03753412 Recruiting Barts & The London NHS Trust 2020-08-01
NCT03714399 Muscle Recovery Following Aortic Surgery Induced ICUAW. https://ClinicalTrials.gov/show/NCT03714399 Recruiting Barts & The London NHS Trust 2020-08-01
NCT03619915 Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients https://ClinicalTrials.gov/show/NCT03619915 Completed Universidade Estadual do Oeste do Paraná 2013-12-31
NCT01047163 Maintenance of Muscle Mass in Older People: the Negative Impact of Statin Therapy https://ClinicalTrials.gov/show/NCT01047163 Completed University of Nottingham 2011-03-31
NCT02021071 Virtual Path Planning for Image-guided Needle Interventions https://ClinicalTrials.gov/show/NCT02021071 Completed Philips Healthcare 2014-06-30
NCT00735384 Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies https://ClinicalTrials.gov/show/NCT00735384 Recruiting University Hospital, Basel, Switzerland 2020-12-31
NCT00588432 Characterization of Skeletal Muscle Using Magnetic Resonance Elastography (MRE) https://ClinicalTrials.gov/show/NCT00588432 Completed Mayo Clinic 2009-09-30
NCT00272883 Molecular and Genetic Studies of Congenital Myopathies https://ClinicalTrials.gov/show/NCT00272883 Recruiting Boston Children’s Hospital 2050-01-31
NCT00004568 Study of Inherited Neurological Disorders https://ClinicalTrials.gov/show/NCT00004568 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT00001331 Genetic and Family Studies of Inherited Muscle Diseases https://ClinicalTrials.gov/show/NCT00001331 Completed National Institutes of Health Clinical Center (CC) NA
NCT00004353 Study of the Metabolism of Pyruvate and Related Problems in Patients With Lactic Acidemia https://ClinicalTrials.gov/show/NCT00004353 Completed National Center for Research Resources (NCRR) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02468895 MYOPROSP - a Prospective Cohort Study in Myositis https://ClinicalTrials.gov/show/NCT02468895 Recruiting University of Manchester 2021-01-31
NCT02398786 Myotonic Dystrophy Family Registry https://ClinicalTrials.gov/show/NCT02398786 Recruiting Myotonic Dystrophy Foundation 2021-02-28
NCT02327364 Natural History of Pearson Syndrome https://ClinicalTrials.gov/show/NCT02327364 Enrolling by invitation The Cleveland Clinic 2020-09-30
NCT02124616 National Registry for Egyptian Pediatric Neuromuscular Diseases https://ClinicalTrials.gov/show/NCT02124616 Recruiting Ain Shams University 2020-04-30
NCT01784679 GNE-Myopathy Disease Monitoring Program (GNEM-DMP): A Registry and Prospective Observational Natural History Study to Assess GNE Myopathy or Hereditary Inclusion Body Myopathy (HIBM) https://ClinicalTrials.gov/show/NCT01784679 Completed Ultragenyx Pharmaceutical Inc 2017-11-30
NCT04064307 Myotubular and Centronuclear Myopathy Patient Registry https://ClinicalTrials.gov/show/NCT04064307 Recruiting Newcastle-upon-Tyne Hospitals NHS Trust 2020-04-30
NCT04043832 A New Method of Muscle Strength Testing Using a Quantitative Ultrasonic Technique and a Convolutional Neural Network https://ClinicalTrials.gov/show/NCT04043832 Completed Peking University Third Hospital 2019-05-15
NCT04020159 Global Registry for COL6-related Dystrophies https://ClinicalTrials.gov/show/NCT04020159 Recruiting Newcastle-upon-Tyne Hospitals NHS Trust 2020-10-31
NCT04009226 International GNE Myopathy Patient Registry https://ClinicalTrials.gov/show/NCT04009226 Recruiting Newcastle University 2020-12-31
NCT01793168 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford https://ClinicalTrials.gov/show/NCT01793168 Recruiting Sanford Health 2100-12-31